ExoticRx · exoticrx.com/drugs/propranolol
US brand names:Inderal
Propranolol is dosed at 0.2–1 mg/kg PO q8-12h in ferrets, per Johnson-Delaney CA. Formulary Ferret Medicine and Surgery, CRC Press, Boca Raton, FL; 2017:457-467. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.947 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.7 (Cardiopulmonary Agents Used in Ferrets). Verify against current literature before clinical use.
Non-selectively blocks beta-1 and beta-2 adrenergic receptors, reducing heart rate, contractility, and blood pressure. Also reduces renin secretion.
CONTRAINDICATED in asthma/bronchospasm (beta-2 blockade). May mask hypoglycemia signs. Bradycardia, hypotension. Do not abruptly discontinue. Reduce dose in hepatic disease.
Species references:All African Grey Parrot drugsAll Dog (Domestic) drugsAll Ferret drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.2–1 mg/kg | q8h | Moderate | Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. doi:10.1111/jvim.15331 — Plumb's 10th ed printed p.1088, Propranolol monograph spanning p.1086-1088. |
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