What is Ticarcillin used for?

Ticarcillin is indicated for: Bacterial infection including Pseudomonas and anaerobes, broad-spectrum bacterial infection, Gram-negative/Pseudomonas and anaerobic infection, Pseudomonal infections, Pseudomonas, Pseudomonas and anaerobes (extended-spectrum penicillin), Pseudomonas infection.

Which species have cited Ticarcillin dosing data?

Ticarcillin dosing in the ExoticRx formulary covers 6 species: African Grey Parrot, Amazon Parrot, Canary, Dog (Domestic), Domestic Pigeon, Zebra Finch.

Is Ticarcillin a controlled substance?

Ticarcillin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

What are the warnings or contraindications for Ticarcillin?

High sodium load. Platelet dysfunction at high doses. Synergistic with aminoglycosides but do not mix in same IV line.

What are the side effects of Ticarcillin?

Reported side effects, adverse reactions, and contraindications for Ticarcillin: High sodium load. Platelet dysfunction at high doses. Synergistic with aminoglycosides but do not mix in same IV line.

How does Ticarcillin work?

Extended-spectrum penicillin with anti-pseudomonal activity. Inhibits cell wall synthesis. Often combined with clavulanate.

Ticarcillin

US brand names:Ticar

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Contraindicated in Rabbit, Guinea Pig, Chinchilla, Hamster, Degu

Rabbit: Oral beta-lactams cause fatal dysbiosis in rabbitsOral amoxicillin (and other oral beta-lactams) selectively destroy gram-positive hindgut flora in rabbits, allowing Clostridium spiroforme overgrowth and fatal enterotoxemia. Never administer oral beta-lactams to rabbits. Parenteral administration carries a lower risk than the oral route, but is not established as safe in rabbits.
Guinea Pig: Oral beta-lactams cause fatal dysbiosis in guinea pigsOral amoxicillin reliably causes Clostridium difficile-mediated fatal enterotoxemia in guinea pigs. Same mechanism as in rabbits. Parenteral administration carries a lower risk than the oral route; parenteral ceftiofur specifically has been given to guinea pigs and chinchillas without adverse effect.
Chinchilla: Oral beta-lactams cause fatal dysbiosis in chinchillasChinchillas are hindgut fermenters with the same flora dependence as rabbits and guinea pigs. Oral penicillins and oral cephalosporins trigger Clostridium overgrowth and fatal enterotoxemia. Never give oral beta-lactams; parenteral routes and trimethoprim-sulfa, fluoroquinolones, or chloramphenicol are the safer choices.

Hamster: Oral beta-lactams cause fatal enterocolitis in hamstersHamsters are exquisitely susceptible to antibiotic-associated Clostridium difficile enterocolitis — the hamster is the classic laboratory model for it. Oral penicillins and cephalosporins are reliably fatal. Never administer oral beta-lactams.

Degu: Oral beta-lactams risk fatal dysbiosis in degusDegus are caviomorph hindgut fermenters closely related to chinchillas and guinea pigs. Degu-specific data is limited, so this warning is extrapolated from those related hystricomorphs — but the shared physiology makes oral beta-lactam enterotoxemia the expected outcome. Treat as contraindicated; use the safer alternatives.

Ticarcillin is dosed at 200 mg/kg IM, IV q6-12h in african grey parrots, per 391. Hawkins MG, Barron H, Speer BL, et al. Birds. In: Carpenter JW, eds. Exotic Animal Formulary, 4th ed., Elsevier Saunders, St. Louis, MO; 2013:183-437. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.421 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Current Therapy in Avian Medicine and Surgery — ISBN 9781455746712, https://openlibrary.org/isbn/9781455746712. Verify against current literature before clinical use.

Backed by 5 published sources

· 241. Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.421 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 391. Hawkins MG, Barron H, Speer BL, et al. Birds. In: Carpenter JW, eds. Exotic Animal Formulary, 4th ed., Elsevier Saunders, St. Louis, MO; 2013:183-437. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.421 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Current Therapy in Avian Medicine and Surgery — ISBN 9781455746712,

Sample dosing (1 of 6 cited rules)

A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	33–50 mg/kg	q4-6h	Weak	Papich, Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Ticarcillin Disodium, printed p.784 (corpus papich p.812) — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855

· 793. Rupley AE. Critical care of pet birds. Vet Clin North Am Exot Anim Pract. 1998;1:11- 41. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.421 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

· Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.421 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Ticarcillin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Ticarcillin dosing data (6 dose rules)

Evidence levels across 6 dose rules

Backed by 5 published sources

Sample dosing (1 of 6 cited rules)

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Ticarcillin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Ticarcillin dosing data (6 dose rules)

Evidence levels across 6 dose rules

Backed by 5 published sources

Sample dosing (1 of 6 cited rules)

Upgrade for Full Details

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