Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tretinoin Topical is used in dog for Comedones / keratinization disorder, Schnauzer comedo syndrome. Routes documented in dog: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Tretinoin Topical in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Retin-A, Tretin-X
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | 0 mg/kg | Apply thin layer q24h-q48h to affected area | 4-8 week trial; chronic if effective | Comedones / keratinization disorder | Weak | Miller WH, Small Animal Dermatology, 7th Ed |
| Topical | 0 mg/kg | Apply to dorsum q24-48h | Chronic maintenance | Schnauzer comedo syndrome | Moderate | Miller WH, Small Animal Dermatology, 7th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
All-trans retinoic acid that binds nuclear retinoic acid receptors (RARs), modulating gene transcription for cell differentiation, proliferation, and keratinization.
Skin irritation and photosensitivity common. Start with lowest concentration. Teratogenic — avoid in breeding animals. Limited veterinary use for comedones and keratinization disorders.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Tretinoin Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.