ExoticRx · exoticrx.com/drugs/cholestyramine
US brand names:Questran, Prevalite
Cholestyramine is dosed at 2 g/rabbit (total dose, NOT g/kg) PO q24h in rabbits, per Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.876 — Plumb's 10th ed printed p.257, Cholestyramine monograph spanning p.257-258. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits). Verify against current literature before clinical use.
Binds bile acids in the intestinal lumen forming an insoluble complex excreted in feces, reducing bile acid reabsorption and lowering cholesterol.
Can bind other oral medications — separate administration by 2 hours. Constipation common. Mix well with liquid before administering.
Species references:All Dog (Domestic) drugsAll Guinea Pig drugsAll Rabbit (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–3 g/dog (NOT g/kg) | PO twice daily (q12h) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed, Cholestyramine monograph, printed p.257-258.Compilation only — we have not located an independent source that prints this figure. |
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