What is Deslorelin Implant used for?

Deslorelin Implant is indicated for: Chemical castration, Chronic egg laying, Ovarian cysts, uterine disease prevention.

Which species have cited Deslorelin Implant dosing data?

Deslorelin Implant dosing in the ExoticRx formulary covers 4 species: African Grey Parrot, Dog (Domestic), Guinea Pig, Rabbit (Domestic).

Is Deslorelin Implant a controlled substance?

Deslorelin Implant is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Deslorelin Implant

US brand names:Suprelorin

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Endocrine

Routes

Indications

Chemical castrationChronic egg layingOvarian cystsuterine disease prevention

Mechanism of Action

GnRH superagonist implant causing initial stimulation then sustained suppression of gonadotropins. Chemical castration lasting 6-12 months.

Side effects & warnings

Used for chemical castration in dogs and exotic species. Also controls adrenal disease in ferrets. Initial hormone flare (1-2 weeks). Duration variable.

Evidence levels across 4 dose rules

Moderate×3Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 4 published sources

· Kohutova S, Jekl V, Knotek Z, et al. The effect of deslorelin acetate on the oestrous cycle of female guinea pigs. Veterinarni Medicina. 2015;60:155-160. doi:10.17221/8062-vetmed — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01).
· SUPRELORIN 4.7 Mg Implant for Dogs [UK Datasheet]. Virbac Limited; 2007.; SUPRELORIN 9.4 Mg Implant for Dogs and Ferrets [UK Datasheet]. Carros, France: Virbac SA; 2010. Distributed by John Wiley & Sons, Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).
· Schoemaker NJ. Gonadotrophin-releasing hormone agonists and other contraceptive medications in exotic companion animals. In: van Zeeland YRA, ed. Vet Clin North Am Exot Anim Pract: Therapeutics. 2018;21:443-464. doi:10.1016/j.cvex.2018.01.011 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.877 (2026-08-01).
· van Zeeland Y. Medication for behavior modification in birds. Vet Clin North Am Exot Anim Pract. 2018;21(1):115-149. doi:10.1016/j.cvex.2017.08.005 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.472 (2026-08-01).

Sample dosing (1 of 4 cited rules)

A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	4.7mg or 9.4mg implant	One implant q6-12 months	Moderate	SUPRELORIN 4.7 Mg Implant for Dogs [UK Datasheet]. Virbac Limited; 2007.; SUPRELORIN 9.4 Mg Implant for Dogs and Ferrets [UK Datasheet]. Carros, France: Virbac SA; 2010. Distributed by John Wiley & Sons, Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).

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