Which species have cited Deslorelin dosing data?

Deslorelin dosing in the ExoticRx formulary covers 8 species: African Grey Parrot, Bearded Dragon, Cat (Domestic), Dog (Domestic), Ferret, Guinea Pig, Pet Rat, Rabbit (Domestic).

Is Deslorelin a controlled substance?

Deslorelin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Deslorelin

US brand names:Suprelorin

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Endocrine

Routes

Indications

Adrenal cortical disease adrenal disease (ferrets)behavior modificationBenign prostatic hyperplasiaChemical castrationChemical sterilizationChronic egg-layingMammary tumour recurrence reduction

Mechanism of Action

Slow-release GnRH agonist implant. Continuous stimulation desensitizes GnRH receptors, suppressing LH and FSH release.

Side effects & warnings

Initial hormone flare for 2-4 weeks. Duration varies by species (6-18 months). May trigger ovulation in some species before suppression. Remove implant to reverse effect.

Evidence levels across 9 dose rules

Moderate×4Strong×2Weak×1Extrapolated×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 9 published sources

· Alkis I, Cetin Y, Sendag S, et al. Long term suppression of oestrus and prevention of pregnancy by deslorelin implant in rats. Bull Vet Inst Pulawy. 2011;55:237-240.; Cetin Y, Alkis I, Sendag S, et al. Long-term effect of deslorelin implant on ovarian pre-antral follicles and uterine histology in female rats. Reprod Domest Anim. 2013;48:195-199. doi:10.1111/j.1439-0531.2012.02128.x — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01).
· Fontaine C (2015) Long-term contraception in a small implant: A review of suprelorin (deslorelin) studies in cats. Journal of Feline Medicine and Surgery 17, 766-771 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.128 (2026-08-01).
· Kohutova S, Jekl V, Knotek Z, et al. The effect of deslorelin acetate on the oestrous cycle of female guinea pigs. Veterinarni Medicina. 2015;60:155-160. doi:10.17221/8062-vetmed — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01).
· Rowland MN. Use of a deslorelin implant to control aggression in a male bearded dragon (Pogona vitticeps). Vet Rec. 2011;169:127. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.260 (2026-08-01).

Sample dosing (2 of 9 cited rules)

A dog/cat sample is shown here. Cited dosing for all 8 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	4.7mg or 9.4mg implant SC	once	Strong	SUPRELORIN 4.7 Mg Implant for Dogs [UK Datasheet]. Virbac Limited; 2007. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).
Cat (Domestic)	SC	Chemical contraception in cats	once	Moderate	Fontaine C (2015) Long-term contraception in a small implant: A review of suprelorin (deslorelin) studies in cats. Journal of Feline Medicine and Surgery 17, 766-771 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.128 (2026-08-01).

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· SUPRELORIN 4.7 Mg Implant for Dogs [UK Datasheet]. Virbac Limited; 2007. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).

· SUPRELORIN 9.4 Mg Implant for Dogs and Ferrets [UK Datasheet]. Carros, France: Virbac SA; 2010. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).

· SUPRELORIN F - Deslorelin Acetate Implant [US Product Label for Ferrets]. Fort Worth, TX: Virbac AH, Inc; 2020. | Carpenter's ref 55: Jepson L. Ferrets. In: Jepson L, eds. Exotic Animal Medicine: A Quick Reference Guide, 2nd ed., Elsevier, St. Louis, MO; 2016:1-42. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aa5776dc-277e-4a5e-885f-6e3f05c8404b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.378 (2026-08-01).

· Schoemaker NJ. Gonadotrophin-releasing hormone agonists and other contraceptive medications in exotic companion animals. In: van Zeeland YRA, ed. Vet Clin North Am Exot Anim Pract: Therapeutics. 2018;21:443-464. doi:10.1016/j.cvex.2018.01.011 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.877 (2026-08-01).

· van Zeeland Y. Medication for behavior modification in birds. Vet Clin North Am Exot Anim Pract. 2018;21(1):115-149. doi:10.1016/j.cvex.2017.08.005 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.472 (2026-08-01).