ExoticRx · exoticrx.com/drugs/everolimus
US brand names:Afinitor
Inhibits mTOR (mammalian target of rapamycin) by binding FKBP-12. Blocks downstream signaling from PI3K/AKT pathway, inhibiting cell growth, proliferation, and angiogenesis.
Immunosuppression — monitor for infections. Stomatitis common. Metabolic effects: hyperglycemia, hyperlipidemia. Non-infectious pneumonitis. Limited veterinary data.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.