ExoticRx · exoticrx.com/drugs/fludarabine
Fludara
Fluorinated nucleotide analogue of vidarabine. Inhibits DNA polymerase alpha, ribonucleotide reductase, and DNA primase. Induces apoptosis in lymphoid cells.
Severe immunosuppression — risk of opportunistic infections. Autoimmune hemolytic anemia. Neurotoxicity at high doses. Limited veterinary data for indolent lymphoid neoplasms.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 15–25 mg/kg | 15-25mg/m2 IV over 30 min q24h x 5 days, q28 days | Anecdotal | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
| Cat (Domestic) | IV | 10–15 mg/kg | 10-15mg/m2 IV q24h x 3 days, q28 days | Anecdotal | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.