ExoticRx · exoticrx.com/drugs/fludarabine
US brand names:Fludara
Fluorinated nucleotide analogue of vidarabine. Inhibits DNA polymerase alpha, ribonucleotide reductase, and DNA primase. Induces apoptosis in lymphoid cells.
Severe immunosuppression — risk of opportunistic infections. Autoimmune hemolytic anemia. Neurotoxicity at high doses. Limited veterinary data for indolent lymphoid neoplasms.
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