Question 1

What routes can Fluorouracil be administered by?

Accepted Answer

Available routes: IV, Topical.

Question 2

Is Fluorouracil a controlled substance?

Accepted Answer

Fluorouracil is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Question 3

What are the warnings or contraindications for Fluorouracil?

Accepted Answer

LETHAL TO CATS — even topical exposure can be fatal. Severe neurotoxicity in cats. In dogs, causes myelosuppression and GI toxicity. Handle with extreme caution.

Question 4

What are the side effects of Fluorouracil?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Fluorouracil: LETHAL TO CATS — even topical exposure can be fatal. Severe neurotoxicity in cats. In dogs, causes myelosuppression and GI toxicity. Handle with extreme caution.

Question 5

How does Fluorouracil work?

Accepted Answer

Converted to active metabolites that inhibit thymidylate synthase, blocking DNA synthesis. Also incorporates into RNA, disrupting RNA processing.

Fluorouracil

Drug Class

Routes

Mechanism of Action

Side effects & warnings

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