ExoticRx · exoticrx.com/drugs/lapatinib
Tykerb
Dual tyrosine kinase inhibitor of EGFR (ErbB1) and HER2 (ErbB2). Blocks downstream MAPK and PI3K/Akt signaling. Investigational in canine mammary carcinoma.
Experimental in veterinary oncology. Hepatotoxicity, GI toxicity, and cardiac effects possible. Monitor liver enzymes. Limited veterinary data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–25 mg/kg | q24h | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
| Cat (Domestic) | PO | 10–25 mg/kg | q24h | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
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