Maropitant Exotic

Mechanism of Action

NK1 receptor antagonist used off-label in exotic species for nausea and visceral pain. Substance P blockade at central and peripheral sites.

Species with Maropitant Exotic dosing data (2 dose rules)

Species references:All Rabbit (Domestic) drugs

Evidence levels across 2 dose rules

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

• · Carpenter's Exotic Animal Formulary, 6th Ed
• · Ozawa SM, Hawkins MG, Drazenovich TL, Kass PH and Knych HK (2019) Pharmacokinetics of maropitant citrate in New Zealand White rabbits (Oryctolagus cuniculus). American Journal of Veterinary Research 80(10), 963-968. | Sadar MJ, McGee WK, Au GG, et al. Pilot pharmacokinetics of a higher dose of subcutaneous maropitant administration in healthy domestic rabbits (Oryctolagus cuniculus). J Exot Pet Med. [Carpenter ref 209a] | NOTE: Carpenter's ref 40 backing the 2 mg/kg q24h row resolves to "Chen S. Personal communication; 2016" - an unpublished personal communication, not a paper. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.891 (2026-08-01).