ExoticRx · exoticrx.com/drugs/panobinostat
US brand names:Farydak
Panobinostat is dosed at 0.5–1 mg/kg PO 3x/week in dogs, per Papich Handbook of Veterinary Drugs, 5th Ed. Verify against current literature before clinical use.
Pan-histone deacetylase (HDAC) inhibitor. Increases histone acetylation, altering gene expression to promote apoptosis and cell cycle arrest in neoplastic cells.
Experimental in veterinary oncology. Severe thrombocytopenia and GI toxicity expected. Monitor CBC closely. Limited veterinary data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | 3x/week | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
| Cat (Domestic) | PO | 0.5–1 mg/kg | 3x/week | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.