Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Pirlimycin (Intramammary) is dosed at 50 mg/quarter INTRAMAMMARY q24h per quarter in cattle, per Pirlimycin - pirlimycin hydrochloride injection, solution [US product label for lactating cattle]. In: Zoetis Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1060 (2026-08-01).. Pirlimycin (Intramammary) is used in cattle for Clinical mastitis (gram-positive), Clinical and subclinical mastitis. Routes documented in cattle: INTRAMAMMARY. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Pirlimycin (Intramammary) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pirsue
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRAMAMMARY | 50 mg/quarter | q24h per quarter | 2-8 days (per label) | Clinical mastitis (gram-positive) | Strong | Pirlimycin - pirlimycin hydrochloride injection, solution [US product label for lactating cattle]. In: Zoetis Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1060 (2026-08-01). |
| INTRAMAMMARY | 50 mg per quartermax 50 mg total | q24h | 2-8 treatments | Clinical and subclinical mastitis | Strong | Pirlimycin - pirlimycin hydrochloride injection, solution [US product label for lactating cattle]. In: Zoetis Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1060 (2026-08-01). |
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Lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Formulated specifically for intramammary infusion.
For treatment of clinical and subclinical mastitis in lactating dairy cattle caused by susceptible staphylococci and streptococci. Observe milk withdrawal period (36 hours). Not for systemic use.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pirlimycin (Intramammary) dose ranges in cattle, with cited source references: INTRAMAMMARY 50 mg/quarter q24h per quarter; INTRAMAMMARY 50 mg per quarter q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pirlimycin (Intramammary) in cattle: INTRAMAMMARY.
Cited course lengths for Pirlimycin (Intramammary) in cattle include: 2-8 days (per label); 2-8 treatments. Duration depends on the indication — match it to the specific dose rule in the table above.
Pirlimycin (Intramammary) is indicated in cattle for: Clinical mastitis (gram-positive), Clinical and subclinical mastitis.
These are general warnings for Pirlimycin (Intramammary) across species; consult the cattle dosing table above for species-specific guidance. For treatment of clinical and subclinical mastitis in lactating dairy cattle caused by susceptible staphylococci and streptococci. Observe milk withdrawal period (36 hours). Not for systemic use.
Why a species-specific page? Pirlimycin (Intramammary) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.