Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Plazomicin is used in dog for CRE / MDR gram-negative infections. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Plazomicin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Zemdri
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–15 mg/kg | q24h | 4-7 days | CRE / MDR gram-negative infections | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds 30S ribosomal subunit. Engineered to resist most aminoglycoside-modifying enzymes, retaining activity against CRE.
Nephrotoxic and ototoxic. TDM recommended. Reserve for carbapenem-resistant Enterobacterales. No veterinary data.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Plazomicin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.