Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pyriproxyfen is dosed at 1–5 mg/kg Topical q30d in dogs, per Product labels (Vectra, Activyl); FDA openFDA Adverse Event Database. Pyriproxyfen is used in dogs for Flea prevention (insect growth regulator). Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pyriproxyfen in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nylar, Vectra
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | 1–5 mg/kg | q30d | Monthly application; year-round in endemic areas | Flea prevention (insect growth regulator) | Strong | Product labels (Vectra, Activyl); FDA openFDA Adverse Event Database |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Juvenile hormone analog that mimics insect juvenile hormone, preventing flea eggs from hatching and larvae from developing into adults. Disrupts the flea life cycle without killing adult fleas.
Extremely low mammalian toxicity. Toxic to aquatic invertebrates — keep treated animals away from water bodies. Does not kill adult fleas; combine with adulticide for complete flea control.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pyriproxyfen dose range in dogs, with cited source references: Topical 1–5 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pyriproxyfen in dogs: Topical.
Cited course lengths for Pyriproxyfen in dogs include: Monthly application; year-round in endemic areas. Duration depends on the indication — match it to the specific dose rule in the table above.
Pyriproxyfen is indicated in dogs for: Flea prevention (insect growth regulator).
These are general warnings for Pyriproxyfen across species; consult the dog dosing table above for species-specific guidance. Extremely low mammalian toxicity. Toxic to aquatic invertebrates — keep treated animals away from water bodies. Does not kill adult fleas; combine with adulticide for complete flea control.
Why a species-specific page? Pyriproxyfen pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.