Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ranolazine is used in dog for Ventricular arrhythmias (adjunct). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ranolazine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ranexa
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–15 mg/kg | q12h | Investigational; monitor QT interval | Ventricular arrhythmias (adjunct) | Weak | Veterinary Cardiology Literature Review |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits late inward sodium current (INaL) during cardiac repolarization, reducing intracellular sodium and calcium overload.
QT prolongation risk. Avoid with strong CYP3A inhibitors. Limited veterinary data — investigational use.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Ranolazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.