Suramin for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Suramin is used in dog for Trypanosomiasis. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Suramin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Germanin, Naganol
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 10–20 mg/kg | Weekly x 3-5 doses | 3-5 weekly IV doses; monitor renal function between doses | Trypanosomiasis | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Polysulfonated naphthylamine that inhibits multiple parasite enzymes including reverse transcriptase and glycolytic enzymes in trypanosomes.
Side effects & warnings
Nephrotoxic — monitor renal function. IV only — causes severe tissue necrosis if given SC/IM. Test dose recommended.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antiparasitic drugs with dog dosing
Suramin dosing in other species
Why a species-specific page? Suramin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.