ExoticRx · exoticrx.com/drugs/thalidomide
US brand names:Thalomid
Thalidomide is dosed at 3–8 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Inhibits angiogenesis (VEGF, bFGF), modulates TNF-alpha, stimulates T-cells, and has direct anti-tumor effects through multiple mechanisms.
SEVERELY TERATOGENIC — strict handling precautions. REMS program in humans. Used investigationally in dogs for hemangiosarcoma and other cancers. Somnolence, neuropathy.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–8 mg/kg | q24h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.