What is Tilmicosin used for?

Tilmicosin is indicated for: Bovine respiratory disease, Pasteurellosis.

Which species have cited Tilmicosin dosing data?

Tilmicosin dosing in the ExoticRx formulary covers 4 species: Cattle (Beef/Dairy), Dog (Domestic), Rabbit (Domestic), Sheep (Ovine).

Is Tilmicosin a controlled substance?

Tilmicosin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Tilmicosin

US brand names:Micotil, Pulmotil

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Tilmicosin is dosed at 25 mg/kg SC once in rabbits, per Plumb's Veterinary Drug Handbook, 10th ed (2023) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.845 — Plumb's 10th ed printed p.1241, Tilmicosin monograph spanning p.1240-1241. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.1 (Antimicrobial Agents Used in Rabbits.a). Verify against current literature before clinical use.

Drug Class

Antibiotic

Routes

SCPO

Indications

Warnings from the source rows

Respiratory infections (NOT RECOMMENDED)

Bovine respiratory diseasePasteurellosis

Mechanism of Action

Semi-synthetic macrolide binding 50S ribosomal subunit. Excellent pulmonary tissue concentration. Bacteriostatic.

Side effects & warnings

FATAL in horses, pigs, and non-human primates — IV injection causes acute cardiac toxicity. Cattle and sheep SC injection only. NOT for use in small animals.

Species with Tilmicosin dosing data (5 dose rules)

Cattle (Beef/Dairy)Dog (Domestic)Rabbit (Domestic)Sheep (Ovine)

Species references:All Cattle (Beef/Dairy) drugs All Dog (Domestic) drugs All Rabbit (Domestic) drugs All Sheep (Ovine) drugs

Evidence levels across 5 dose rules

Moderate×2Anecdotal×1Weak×1Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Sample dosing (1 of 5 cited rules)

A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	POTENTIALLY FATAL in small animals	NOT RECOMMENDED	Anecdotal	Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791Compilation only — we have not located an independent source that prints this figure.

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Backed by 3 published sourcesShow

· MICOTIL 300- Tilmicosin Phosphate Injection [Product Label]. Elanco US Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=08f1aecd-33c2-457b-8a45-c38fafb3a1c7 — Plumb's 10th ed printed p.1241, Tilmicosin monograph spanning p.1240-1241. — 21 CFR § 522.2471 (Tilmicosin), conditions of use for Sheep: 10-10 mg/kg. Related tolerances: 21 CFR § 556.735. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.2471
· Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791
· Plumb's Veterinary Drug Handbook, 10th ed (2023) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.845 — Plumb's 10th ed printed p.1241, Tilmicosin monograph spanning p.1240-1241. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.1 (Antimicrobial Agents Used in Rabbits.a).

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Calculate Dosage for Tilmicosin