ExoticRx · exoticrx.com/drugs/tiopronin
Thiola
Thiol compound that forms disulfide bond with cysteine producing a more soluble mixed disulfide compound. Reduces cystine stone formation.
Used for cystine urolithiasis prevention. GI upset, proteinuria. Monitor CBC and urinalysis. Better tolerated than D-penicillamine for cystinuria.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 15–30 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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