ExoticRx · exoticrx.com/drugs/trientine
US brand names:Syprine
Trientine is dosed at 10 mg/kg PO q12h in ferrets, per Jepson L. Ferrets. In: Jepson L, eds. Exotic Animal Medicine: A Quick Reference Guide, 2nd ed., Elsevier, St. Louis, MO; 2016:1-42. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.959 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.10 (Miscellaneous Agents Used in Ferrets.a). Verify against current literature before clinical use.
Chelates copper by forming a stable complex excreted in urine. Alternative to penicillamine for copper storage disease.
Less toxic than penicillamine. Give on empty stomach. May cause iron deficiency with chronic use.
Species references:All Dog (Domestic) drugsAll Ferret drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–15 mg/kg | q12h | Moderate | Twedt D. Canine chronic hepatitis. WVC; 2012. — Plumb's 10th ed printed p.1274, Trientine monograph.Compilation only — we have not located an independent source that prints this figure. |
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