ExoticRx · exoticrx.com/drugs/trientine
US brand names:Syprine
Trientine is dosed at 10 mg/kg PO q12h in ferrets, per Jepson L. Ferrets. In: Jepson L, eds. Exotic Animal Medicine: A Quick Reference Guide, 2nd ed., Elsevier, St. Louis, MO; 2016:1-42. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.959 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.10 (Miscellaneous Agents Used in Ferrets.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Chelates copper by forming a stable complex excreted in urine. Alternative to penicillamine for copper storage disease.
Less toxic than penicillamine. Give on empty stomach. May cause iron deficiency with chronic use.
Species references:All Dog (Domestic) drugsAll Ferret drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–15 mg/kg | q12h | Moderate | Twedt D. Canine chronic hepatitis. WVC; 2012. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1302 (2026-08-01). — Plumb's 10th ed (held) printed p.1274, Trientine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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