Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Tulathromycin (Long-Acting) is dosed at 2.5 mg/kg SC single dose in cattle, per DRAXXIN - Tulathromycin Injection, Solution [US Product Label for Beef Cattle, Nonlactating Dairy Cattle, Veal Calves, and Swine]. Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=044385d5-c9eb-4a44-9ffd-2b68092262fe — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1310 (2026-08-01). — Plumb's 10th ed (held) printed p.1283, Tulathromycin monograph spanning p.1282-1283; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — 21 CFR § 522.2630 (Tulathromycin), conditions of use for Cattle: 2.5-2.5 mg/kg. Related tolerances: 21 CFR § 556.745. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.2630 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Tulathromycin (Long-Acting) is used in cattle for Bovine respiratory disease. Routes documented in cattle: SC. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Tulathromycin (Long-Acting) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Draxxin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 2.5 mg/kg | single dose | Bovine respiratory disease | Strong | DRAXXIN - Tulathromycin Injection, Solution [US Product Label for Beef Cattle, Nonlactating Dairy Cattle, Veal Calves, and Swine]. Zoetis Inc.; 2020. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=044385d5-c9eb-4a44-9ffd-2b68092262fe — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1310 (2026-08-01). — Plumb's 10th ed (held) printed p.1283, Tulathromycin monograph spanning p.1282-1283; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — 21 CFR § 522.2630 (Tulathromycin), conditions of use for Cattle: 2.5-2.5 mg/kg. Related tolerances: 21 CFR § 556.745. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.2630 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2.5 | SC | Papich Saunders Handbook of Veterinary Drugs, 4th edp.853 | • 2.5 mg/kg SQ (neck) as a single injection (1.1 mL per 100 pounds for 100-mg/ |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Semi-synthetic triamilide macrolide that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Concentrates in pulmonary tissue providing prolonged lung concentrations from a single injection.
Single SC injection only. Do not inject IV. Tissue reactions at injection site. Not for use in lactating dairy cattle. Do not inject more than 10ml per site in cattle.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tulathromycin (Long-Acting) dose range in cattle, with cited source references: SC 2.5 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tulathromycin (Long-Acting) in cattle: SC.
Tulathromycin (Long-Acting) is indicated in cattle for: Bovine respiratory disease.
These are general warnings for Tulathromycin (Long-Acting) across species; consult the cattle dosing table above for species-specific guidance. Single SC injection only. Do not inject IV. Tissue reactions at injection site. Not for use in lactating dairy cattle. Do not inject more than 10ml per site in cattle.
Why a species-specific page? Tulathromycin (Long-Acting) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.