What is Clotrimazole used for?

Clotrimazole is indicated for: Dermatophytosis, Malassezia, Sinus aspergillosis (topical flush).

Which species have cited Clotrimazole dosing data?

Clotrimazole dosing in the ExoticRx formulary covers 3 species: African Grey Parrot, Cat (Domestic), Dog (Domestic).

Is Clotrimazole a controlled substance?

Clotrimazole is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

What are the side effects of Clotrimazole?

Reported side effects, adverse reactions, and contraindications for Clotrimazole: Topical use only. Low systemic absorption. May cause local irritation. Effective against dermatophytes and Malassezia.

Clotrimazole

US brand names:Lotrimin

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antifungal

Routes

Topical

Indications

DermatophytosisMalasseziaSinus aspergillosis (topical flush)

Mechanism of Action

Inhibits ergosterol synthesis by blocking lanosterol 14-alpha demethylase. Disrupts fungal cell membrane integrity.

Side effects & warnings

Topical use only. Low systemic absorption. May cause local irritation. Effective against dermatophytes and Malassezia.

Species with Clotrimazole dosing data (3 dose rules)

African Grey Parrot Cat (Domestic)Dog (Domestic)

Species references:All African Grey Parrot drugs All Cat (Domestic) drugs All Dog (Domestic) drugs

Evidence levels across 3 dose rules

Strong×1Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 3 published sources

· Phalen DN. Common bacterial and fungal infectious diseases in pet birds. Suppl Compend Contin Educ Pract Vet. 2003;25:43-48. PMID: 21872782 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.424 (2026-08-01).
· Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1461 (2026-08-01).
· Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1462 (2026-08-01).

Sample dosing (2 of 3 cited rules)

A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	Topical	Apply thin layer to affected area	q12h	Strong	Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1461 (2026-08-01).
Cat (Domestic)	Topical	Apply to affected area	q12h	Moderate	Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1462 (2026-08-01).

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Other formulations of Clotrimazole

Calculate Dosage for Clotrimazole