ExoticRx · exoticrx.com/drugs/cytarabine
US brand names:Cytosar-U
Cytarabine is dosed at 50 mg/m2 SC SC q12h x 2 days, repeat q3 weeks in dogs, per Zarfoss M, Schatzberg S, Venator K, et al. Combined cytosine arabinoside and prednisone therapy for meningoencephalitis of unknown aetiology in 10 dogs. J Small Anim Pract. 2006;47(10):588-595. doi:10.1111/j.1748-5827.2006.00172.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.358 (2026-08-01).. Verify against current literature before clinical use.
Converted to ara-CTP which inhibits DNA polymerase and incorporates into DNA causing chain termination. S-phase specific.
Used for lymphoma/leukemia protocols and GME. Myelosuppression dose-limiting. SC CRI protocol for GME (cytarabine arabinoside). Handle with chemotherapy precautions.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 50 mg/m2 | SC q12h x 2 days, repeat q3 weeks | Moderate | Zarfoss M, Schatzberg S, Venator K, et al. Combined cytosine arabinoside and prednisone therapy for meningoencephalitis of unknown aetiology in 10 dogs. J Small Anim Pract. 2006;47(10):588-595. doi:10.1111/j.1748-5827.2006.00172.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.358 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.