Danofloxacin for Cattle
Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Danofloxacin is used in cattle for Bovine respiratory disease (BRD). Routes documented in cattle: SC. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Danofloxacin in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Advocin, A180
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 6–8 mg/kg | q24h | 8mg/kg single or 6mg/kg x 3 days | Bovine respiratory disease (BRD) | Strong | FDA NADA Label |
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal activity against gram-negative and some gram-positive organisms.
Side effects & warnings
Avoid in growing animals (cartilage damage risk). Not for use in lactating dairy cattle. Injection site reactions possible. Avoid concurrent use with cation-containing products.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with cattle dosing
Danofloxacin dosing in other species
Why a species-specific page? Danofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.