Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Danofloxacin is used in dog for Severe gram-negative bacterial infections. Routes documented in dog: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Danofloxacin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Advocin, A180
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 1.25–2.5 mg/kg | q24h | 3-5 days | Severe gram-negative bacterial infections | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal activity against gram-negative and some gram-positive organisms.
Avoid in growing animals (cartilage damage risk). Not for use in lactating dairy cattle. Injection site reactions possible. Avoid concurrent use with cation-containing products.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Danofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.