Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Daptomycin is used in dog for Resistant gram-positive infections (MRSA/MRSP). Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Daptomycin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cubicin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q24h | 7-14 days | Resistant gram-positive infections (MRSA/MRSP) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds to bacterial cell membranes causing rapid depolarization, loss of membrane potential, and cell death.
Monitor CPK levels for myopathy. Not effective for pneumonia (inactivated by surfactant). Renal dose adjustment needed.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Daptomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.