Cat · Felis catus · typical adult weight 2.50–7.00 kg
Dexrazoxane is used in cat for Cardioprotection during doxorubicin therapy. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Dexrazoxane in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Zinecard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 250 mg/kg | 10:1 ratio to dox, IV before dox | Each doxorubicin cycle | Cardioprotection during doxorubicin therapy | Weak | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Intracellularly hydrolyzed to open-ring form that chelates iron, preventing iron-mediated free radical generation responsible for doxorubicin cardiotoxicity.
Administered 15-30 minutes before doxorubicin. 10:1 ratio (dexrazoxane:doxorubicin). May slightly increase myelosuppression. Used to extend cumulative doxorubicin dose limits.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Dexrazoxane pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.