Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Eplerenone is dosed at 0.5–2 mg/kg PO q12-24h in dogs, per Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use.. Eplerenone is used in dogs for Heart failure adjunct / aldosterone antagonism. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Eplerenone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Inspra
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12-24h | Long-term; monitor potassium | Heart failure adjunct / aldosterone antagonism | Weak | Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective mineralocorticoid receptor antagonist that blocks aldosterone at the receptor level, reducing sodium reabsorption and potassium excretion without anti-androgenic effects.
Monitor potassium — hyperkalemia risk. Avoid with potassium-sparing diuretics. Less gynecomastia than spironolactone.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Eplerenone dose range in dogs, with cited source references: PO 0.5–2 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Eplerenone in dogs: PO.
Cited course lengths for Eplerenone in dogs include: Long-term; monitor potassium. Duration depends on the indication — match it to the specific dose rule in the table above.
Eplerenone is indicated in dogs for: Heart failure adjunct / aldosterone antagonism.
These are general warnings for Eplerenone across species; consult the dog dosing table above for species-specific guidance. Monitor potassium — hyperkalemia risk. Avoid with potassium-sparing diuretics. Less gynecomastia than spironolactone.
Why a species-specific page? Eplerenone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.