ExoticRx · exoticrx.com/drugs/grapiprant
Galliprant
Selectively blocks the EP4 prostaglandin receptor, the primary mediator of osteoarthritis pain and inflammation, without broadly inhibiting COX enzymes.
Dogs only. Novel mechanism — does not broadly inhibit prostaglandin synthesis. Vomiting is most common adverse effect. Not for use with other NSAIDs.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2 mg/kg | q24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.