Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Isosorbide Mononitrate is used in dog for Congestive heart failure (preload reduction). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Isosorbide Mononitrate in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Imdur, Monoket
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12-24h (ER formulation) | Long-term; eccentric dosing to avoid tolerance | Congestive heart failure (preload reduction) | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Active metabolite of isosorbide dinitrate that releases nitric oxide, dilating venous capacitance vessels and reducing cardiac preload.
Similar to isosorbide dinitrate but with more predictable oral bioavailability. Tolerance still develops. Hypotension possible.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Isosorbide Mononitrate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.