ExoticRx · exoticrx.com/drugs/phenylbutazone
US brand names:Butazolidin
Phenylbutazone is dosed at 3.5–7 mg/kg PO q8-12h in african grey parrots, per 255. Edling TM. Anaesthesia and analgesia. In: Chitty J, Harcourt-Brown N, eds. BSAVA Manual of Psittacine Birds; British Small Animal Veterinary Association, Gloucester, UK; 2005:87-96. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.460 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.6 (Nonsteroidal Antiinflammatory Agents Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Non-selective COX inhibitor with potent anti-inflammatory and analgesic properties.
High toxicity in dogs (bone marrow aplasia, GI ulceration). Primarily used in horses and dogs. NEVER use in cats. Perivascular injection causes severe tissue necrosis.
Species references:All African Grey Parrot drugsAll Dog (Domestic) drugsAll Green-cheeked Conure drugsAll Horse (Equine) drugsAll Umbrella Cockatoo drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 5 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–10 mg/kg | q12h; 7d then reduce; max 800 mg/dog/day | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1013, Phenylbutazone monograph spanning p.1013-1014; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — DAILY CEILING: Plumb's Veterinary Drug Handbook, Phenylbutazone monograph, printed p.1041 — "14.7 mg/kg PO 3 times daily initially (maximum of 800 mg/dog [NOT mg/kg] daily regardless of weight)". Corroborated by the FDA-approved label (DailyMed) — "not to exceed 800 mg daily regardless of body weight" — and by the AAVPT monograph. This is a PER-DAY limit, enforced via max_dose_mg_per_day. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.