ExoticRx · exoticrx.com/drugs/phenylbutazone
US brand names:Butazolidin
Phenylbutazone is dosed at 3–8 mg/kg PO q8-12h (max 3 days) in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Non-selective COX inhibitor with potent anti-inflammatory and analgesic properties.
High toxicity in dogs (bone marrow aplasia, GI ulceration). Primarily used in horses and dogs. NEVER use in cats. Perivascular injection causes severe tissue necrosis.
Species references:All Dog (Domestic) drugsAll Horse (Equine) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–8 mg/kg | q8-12h (max 3 days) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.