ExoticRx · exoticrx.com/drugs/proparacaine-ophthalmic
US brand names:Alcaine, Proparacaine HCl
Ester-type local anesthetic that stabilizes neuronal membranes by inhibiting sodium ion channels, preventing initiation and transmission of nerve impulses from the corneal surface.
Onset within 20 seconds, duration 15-20 minutes. Repeated use causes corneal epithelial toxicity. Never dispense for at-home use. Store refrigerated.
Species references:All Bearded Dragon drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Standard ophthalmic examination anesthetic | 1-2 drops; onset 20 sec, duration 15-20 min | Strong | Herring et al., 2005 (cited in text; Gelatt 6th ed., printed p.568) — Verified against Veterinary Ophthalmology (Gelatt), 6th Ed, p.591 (2026-08-01). |
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