ExoticRx · exoticrx.com/drugs/ranitidine
US brand names:Zantac
Ranitidine is dosed at 2–5 mg/kg PO q12h in rabbits, per Oglesbee B, Lord B. Gastrointestinal diseases of rabbits. In: Quesenberry KE, Orcutt CJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:174-187. doi:10.1016/b978-0-323-48435-0.00014-9 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.880 (2026-08-01).. Verify against current literature before clinical use.
Competitively blocks H2 receptors on parietal cells, reducing gastric acid secretion. Also has prokinetic activity via acetylcholinesterase inhibition.
Less drug interaction potential than cimetidine. Prokinetic effect makes it preferred over famotidine when motility enhancement also desired. Administer slowly IV. Note: human formulation withdrawn in some markets.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Rabbit (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 2.5–3.5 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | PO | 2 mg/kg | q8-12h | Moderate | Bersenas AME. Antacid therapy. In: Bonagura JD, Twedt DC, eds. Kirk’s Current Veterinary Therapy XV. St. Louis, MO: Elsevier Saunders; 2014. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1140 (2026-08-01). |
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