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Solithromycin for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Solithromycin is used in dog for Respiratory / resistant infections. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Solithromycin in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: CEM-101

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–10 mg/kgq24h5-7 daysRespiratory / resistant infectionsWeakPlumb's Veterinary Drug Handbook, 9th Ed

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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Binds 50S ribosomal subunit at three sites (vs. two for older macrolides). Overcomes macrolide resistance. Bacteriostatic.

Side effects & warnings

Hepatotoxicity risk. QTc minimal. GI upset less than erythromycin. No veterinary data.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with dog dosing

Solithromycin dosing in other species

Why a species-specific page? Solithromycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.