Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Sulfadimethoxine is dosed at 55 mg/kg PO 55 mg/kg day 1, then 27.5 mg/kg q24h; max 5 days in cattle, per ALBON BOLUS- Sulfadimethoxine Tablet [US Product Label for Cattle]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=adc0eb45-6378-4702-817a-764ddb5ae605 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1226 (2026-08-01). — Plumb's 10th ed (held) printed p.1199, Sulfadimethoxine monograph spanning p.1197-1199; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — 21 CFR § 522.2220 (Sulfadimethoxine), conditions of use for Cattle: 55.1156-55.1156 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.640. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.2220 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Sulfadimethoxine is used in cattle for Shipping fever / bacterial pneumonia (Pasteurella spp); calf diphtheria and foot rot (Fusobacterium necrophorum). Routes documented in cattle: PO. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Sulfadimethoxine in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Albon
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 55 mg/kg | 55 mg/kg day 1, then 27.5 mg/kg q24h; max 5 days | 5 days | Shipping fever / bacterial pneumonia (Pasteurella spp); calf diphtheria and foot rot (Fusobacterium necrophorum) | Strong | ALBON BOLUS- Sulfadimethoxine Tablet [US Product Label for Cattle]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=adc0eb45-6378-4702-817a-764ddb5ae605 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1226 (2026-08-01). — Plumb's 10th ed (held) printed p.1199, Sulfadimethoxine monograph spanning p.1197-1199; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — 21 CFR § 522.2220 (Sulfadimethoxine), conditions of use for Cattle: 55.1156-55.1156 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.640. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-522.2220 — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 55 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.779 | • Treatment of pneumonia and other infections: 55 mg/kg as initial dose, followed |
| 27 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.779 | by 27 mg/kg q24h PO for 5 days. |
| 137.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.779 | • Sustained-release bolus (Albon-SR): 137.5 mg/kg PO as a single dose. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits dihydropteroate synthase in the folate synthesis pathway. Long-acting sulfonamide with bacteriostatic activity.
Ensure adequate hydration (crystalluria risk). Monitor CBC with prolonged use. KCS risk in dogs. Avoid in animals with hepatic disease.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sulfadimethoxine dose range in cattle, with cited source references: PO 55 mg/kg 55 mg/kg day 1, then 27.5 mg/kg q24h; max 5 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sulfadimethoxine in cattle: PO.
Cited course lengths for Sulfadimethoxine in cattle include: 5 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Sulfadimethoxine is indicated in cattle for: Shipping fever / bacterial pneumonia (Pasteurella spp); calf diphtheria and foot rot (Fusobacterium necrophorum).
These are general warnings for Sulfadimethoxine across species; consult the cattle dosing table above for species-specific guidance. Ensure adequate hydration (crystalluria risk). Monitor CBC with prolonged use. KCS risk in dogs. Avoid in animals with hepatic disease.
Why a species-specific page? Sulfadimethoxine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.