Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Sulfadimethoxine is dosed at 50 mg/kg PO once, then 25 mg/kg PO q24h x 10-20 days in rabbits, per Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). Verify against current literature before clinical use.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 30 cited rules)
A dog/cat sample is shown here. Cited dosing for all 28 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Species
Route
Dose
Frequency
Evidence
Source
Dog (Domestic)
PO
55 mg/kg
q24h (loading), then q24h maintenance at half dose
Plumb's Veterinary Drug Handbook 10th ed., Sulfadimethoxine, Dosages > DOGS/CATS, printed p.1198; ref 15 = ALBON - Sulfadimethoxine Tablet [US Product Label for Dogs and Cats]. Zoetis; 2019 — DURATION, from the FDA ALBON label (NADA 015-102 / 043-785): "Length of treatment depends on the clinical response. In most cases treatment for 3-5 days is […]" The label prints no fixed 10-14 day course; that figure was not sourced.
· 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.780
· 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.780 — Carpenter 6th ed, Table 9.2 (Antiparasitic Agents Used in Rodents), MIDDLE sulfadimethoxine sub-row bearing superscript 130.
· 168. Klingenberg RJ. Understanding Reptile Parasites. Irvine, CA: Advanced Vivarium Systems; 2007:1-200. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1407
· 232. Doneley B. Formulary. In: Doneley B, eds. Avian Medicine and Surgery in Practice: Companion and Aviary Birds; Manson Publishing, London, UK; 2011:285-320. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.443 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.4 (Antiparasitic Agents Used in Birds).
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· Avian Medicine: Principles and Application (Ritchie, Harrison & Harrison), p.821. Row as printed binds this dose to raptors on its own line: "Sulfadimethoxine 25 mg/kg PO q12h ! 5 days Raptors".
· Bell JA. Periparturient and neonatal diseases. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 2nd ed., WB Saunders, St. Louis, MO; 2004:50-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.938 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.4 (Antiparasitic Agents Used in Ferrets).
· Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).
· FARAD Withdrawal Guidelines — dose corroborated 2026-08-05 in Plumb's Veterinary Drug Handbook 10th ed, Sulfadimethoxine monograph, printed p.1198. NOTE: FARAD publishes meat/milk WITHDRAWAL intervals for extralabel use; it is not the source of the dose itself, so the dose is cited to Plumb's and FARAD retained for the withdrawal guidance.
· Morrisey JK, Carpenter JW, et al. Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.933 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.1 (Antimicrobial Agents Used in Ferrets). — ATTRIBUTION: the regimen is printed by Carpenter 6th ed, Table 11.1 (Antimicrobial Agents Used in Ferrets), row "Sulfadimethoxine 25 mg/kg PO, SC, IM q24h88" with an empty Comments cell. The NAMED PRIMARY does not print it - Ferrets Rabbits and Rodents 4th ed carries no sulfadimethoxine row in Table A.1 at all, and its only ferret entry is Table A.3, printed p.625, "50 mg/kg PO once, then 25 mg/kg q24h x 10 days". BSAVA Small Animal Formulary Part B printed p.275 prints "Ferrets: 50 mg/kg p.o. once, then 25 mg/kg p.o. q24h for 5-10 days". Both upstream texts bound the course and frame the drug as an anticoccidial, and Carpenter ferret Table 11.4 prints "Sulfadimethoxine 20-50 mg/kg PO q24h - Coccidia". UNSOURCED AT THE NAMED PRIMARY, not unsafe.
· Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.780
· Plumb's Veterinary Drug Handbook 10th ed., Sulfadimethoxine, Dosages > DOGS/CATS, printed p.1198; ref 15 = ALBON - Sulfadimethoxine Tablet [US Product Label for Dogs and Cats]. Zoetis; 2019 — DURATION, from the FDA ALBON label (NADA 015-102 / 043-785): "Length of treatment depends on the clinical response. In most cases treatment for 3-5 days is […]" The label prints no fixed 10-14 day course; that figure was not sourced.
· Rockwell K, Mitchell MM. Antiparasitic therapy. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1165-1170. — Carpenter's Exotic Animal Formulary 6th ed, Table 4.4 (Antiparasitic Agents Used in Reptiles).