ExoticRx · exoticrx.com/drugs/terbinafine-oral
US brand names:Lamisil
Terbinafine Oral is dosed at 20–30 mg/kg PO q24h in dogs, per Greene CE. Infectious Diseases of the Dog and Cat, ed 3, Philadelphia, 2006, W.B. Saunders Co. — Muller & Kirk's Small Animal Dermatology, 7th Ed, p.229. Verify against current literature before clinical use.
Inhibits squalene epoxidase in ergosterol synthesis. Fungicidal against dermatophytes. Concentrates in skin, nails, and hair.
Hepatotoxicity — monitor liver enzymes. GI upset. Drug interactions (CYP2D6 inhibitor). Effective for dermatophytosis resistant to azoles. Excellent keratin concentration.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 20–30 mg/kg | q24h | Moderate | Greene CE. Infectious Diseases of the Dog and Cat, ed 3, Philadelphia, 2006, W.B. Saunders Co. — Muller & Kirk's Small Animal Dermatology, 7th Ed, p.229Compilation only — we have not located an independent source that prints this figure. |
| Cat (Domestic) | PO | 30–40 mg/kg | q24h | Weak | Papich, Saunders Handbook of Veterinary Drugs, Terbinafine Hydrochloride, printed p.765, Small Animal Dosage/Cats: "30-40 mg/kg/day PO for at least 2 weeks." Second source: BSAVA Small Animal Formulary 10th ed, Part A, printed p.394: "Dogs, Cats: Antifungal: 20-40 mg/kg p.o. q24h."Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.