Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Vigabatrin is used in dog for Refractory epilepsy (last resort). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Vigabatrin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Sabril
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 25–50 mg/kg | q12h | Chronic use; requires visual field monitoring | Refractory epilepsy (last resort) | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Irreversible inhibitor of GABA-transaminase, the enzyme responsible for GABA catabolism. Increases GABA concentration in the brain.
Risk of permanent bilateral visual field defects. Requires visual field monitoring. Reserved for refractory cases. Very limited veterinary use.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Vigabatrin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.