Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Carbidopa-Levodopa is used in dog for Investigational for movement disorders. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Carbidopa-Levodopa in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Sinemet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q8h (levodopa component) | Duration based on clinical response | Investigational for movement disorders | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Levodopa is converted to dopamine in the CNS. Carbidopa inhibits peripheral DOPA decarboxylase, reducing peripheral side effects and increasing CNS levodopa availability.
GI upset common. May cause behavioral changes, dyskinesia. Very limited veterinary use — primarily investigational for movement disorders.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Carbidopa-Levodopa pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.