ExoticRx · exoticrx.com/drugs/firocoxib
US brand names:Previcox, Equioxx
Firocoxib is dosed at 10–20 mg/kg IP q24h in mice, per 143. Reddyjarugu B, Pavek T, Southard T, et al. Analgesic efficacy of firocoxib, a selective inhibitor of cyclooxygenase 2, in a mouse model of incisional pain. J Am Assoc Lab Anim Sci. 2015;54:405-410. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.791 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.4 (Analgesic Agents Used in Rodents). Verify against current literature before clinical use.
Highly selective COX-2 inhibitor, reducing prostaglandin-mediated inflammation and pain.
Dogs only (not approved for cats). GI adverse effects. Monitor hepatic and renal function. Not for use with other NSAIDs.
Species references:All Dog (Domestic) drugsAll Mouse drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5 mg/kg | q24h | Strong | Previcox® [product label]. Duluth, GA: Merial; 2012.; Kondo Y, Takashima K, Matsumoto S, et al. Efficacy and safety of firocoxib for the treatment of pain associated with soft tissue surgery in dogs under field conditions in Japan. J Vet Med Sci. 2012;74(10):1283-1289. doi:10.1292/jvms.11-0306; Davila D, Keeshen TP, Evans RB, Conzemius MG. Comparison of the analgesic efficacy of perioperative firocoxib and tramadol administration in dogs undergoing tibial plateau leveling osteotomy. J Am Vet Med Assoc. 2013;243(2):225-231. doi:10.2460/javma.243.2.225 — Plumb's 10th ed printed p.527, Firocoxib monograph spanning p.525-527. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.