ExoticRx · exoticrx.com/drugs/masitinib
US brand names:Masivet, Kinavet
Masitinib is dosed at 12.5 mg/kg PO q24h in dogs, per Hahn KA, Oglivie G, Rusk T et al. (2008) Masitinib is safe and effective for the treatment of canine mast cell tumours. Journal of Veterinary Internal Medicine 22, 1301-1309 doi:10.1111/j.1939-1676.2008.0190.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.262 (2026-08-01).. Verify against current literature before clinical use.
Selectively inhibits c-Kit receptor tyrosine kinase, PDGFR, and Lyn kinase. Targets mast cell tumor growth signaling. Also inhibits FGFR3.
Approved for non-resectable grade II/III mast cell tumors with confirmed c-Kit mutation. GI upset, neutropenia, protein-losing nephropathy. Monitor CBC and urinalysis.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 12.5 mg/kg | q24h | Moderate | Hahn KA, Oglivie G, Rusk T et al. (2008) Masitinib is safe and effective for the treatment of canine mast cell tumours. Journal of Veterinary Internal Medicine 22, 1301-1309 doi:10.1111/j.1939-1676.2008.0190.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.262 (2026-08-01). |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.