Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Nintedanib is dosed at 2–5 mg/kg PO q12h in dogs, per Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use.. Nintedanib is used in dogs for Idiopathic pulmonary fibrosis. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Nintedanib in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Ofev
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q12h | Long-term; investigational | Idiopathic pulmonary fibrosis | Weak | Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Triple angiokinase inhibitor blocking VEGFR, FGFR, and PDGFR tyrosine kinases, reducing fibroblast migration, proliferation, and extracellular matrix deposition.
Diarrhea most common side effect. Hepatotoxicity risk — monitor LFTs. Bleeding risk. Investigational for pulmonary fibrosis in dogs.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Nintedanib dose range in dogs, with cited source references: PO 2–5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Nintedanib in dogs: PO.
Cited course lengths for Nintedanib in dogs include: Long-term; investigational. Duration depends on the indication — match it to the specific dose rule in the table above.
Nintedanib is indicated in dogs for: Idiopathic pulmonary fibrosis.
These are general warnings for Nintedanib across species; consult the dog dosing table above for species-specific guidance. Diarrhea most common side effect. Hepatotoxicity risk — monitor LFTs. Bleeding risk. Investigational for pulmonary fibrosis in dogs.
Why a species-specific page? Nintedanib pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.