Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Nintedanib is used in dog for Idiopathic pulmonary fibrosis. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Nintedanib in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ofev
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q12h | Long-term; investigational | Idiopathic pulmonary fibrosis | Weak | Veterinary Pulmonology Literature Review |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Triple angiokinase inhibitor blocking VEGFR, FGFR, and PDGFR tyrosine kinases, reducing fibroblast migration, proliferation, and extracellular matrix deposition.
Diarrhea most common side effect. Hepatotoxicity risk — monitor LFTs. Bleeding risk. Investigational for pulmonary fibrosis in dogs.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Nintedanib pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.