Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pirfenidone is used in dog for Idiopathic pulmonary fibrosis. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pirfenidone in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Esbriet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–25 mg/kg | q8h | Long-term; months; monitor LFTs | Idiopathic pulmonary fibrosis | Weak | Veterinary Pulmonology Literature Review |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Antifibrotic agent that reduces TGF-beta, PDGF, and TNF-alpha production, inhibiting fibroblast proliferation, collagen deposition, and pulmonary fibrosis progression.
Photosensitivity — limit sun exposure. GI upset, rash, elevated LFTs. Investigational for canine idiopathic pulmonary fibrosis.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Pirfenidone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.