ExoticRx · exoticrx.com/drugs/pyrantel-pamoate
US brand names:Strongid-T, Nemex
Pyrantel Pamoate is dosed at 5–10 mg/kg PO Single dose, repeat in 2-3 weeks in dogs, per Nemex 2 Non-Sterile - Pyrantel Pamoate Suspension [US Product Label for Dogs]. Zoetis; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d6dcd1-7835-4c7b-bbae-d14752d9983b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1120 (2026-08-01).. Verify against current literature before clinical use.
Depolarizing neuromuscular blocking agent in nematodes. Causes spastic paralysis of susceptible worms.
Very safe — poorly absorbed from GI tract. Effective against roundworms and hookworms. Do not combine with organophosphates or morantel (same mechanism). Safe in puppies from 2 weeks.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Horse (Equine) drugsAll Swine (Pig) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–10 mg/kg | Single dose, repeat in 2-3 weeks | Strong | Nemex 2 Non-Sterile - Pyrantel Pamoate Suspension [US Product Label for Dogs]. Zoetis; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d6dcd1-7835-4c7b-bbae-d14752d9983b — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1120 (2026-08-01). |
| Cat (Domestic) | PO | 5–10 mg/kg | Single dose, repeat in 2-3 weeks | Strong | Hoskins J. Veterinary pediatrics of the puppy and kitten. Presented at: Atlantic Coast Veterinary Conference; 2006. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1120 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.