Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Rasburicase is used in dog for Tumor lysis syndrome/Severe hyperuricemia. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Rasburicase in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Elitek, Fasturtec
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.05–0.2 mg/kg | Single dose, may repeat q24h x 1-3 days | 1-3 doses based on uric acid response | Tumor lysis syndrome/Severe hyperuricemia | Weak | JVIM Case Reports; Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Recombinant urate oxidase that catalyzes oxidation of uric acid to allantoin, a highly soluble metabolite easily excreted renally.
Anaphylaxis risk — monitor during infusion. Contraindicated in G6PD-deficient animals. Extremely expensive. Destroys uric acid in blood samples.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Rasburicase pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.