Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sodium Polystyrene Sulfonate is used in dog for Hyperkalemia. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Sodium Polystyrene Sulfonate in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Kayexalate, Kionex
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 500–1000 mg/kg | q8-12h | Short-term until hyperkalemia resolves; transition to definitive therapy | Hyperkalemia | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Cation exchange resin that exchanges sodium for potassium in the GI tract, increasing fecal potassium excretion and lowering serum potassium.
Risk of sodium overload in cardiac patients. Intestinal necrosis reported with sorbitol. Monitor electrolytes closely. Constipation common.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Sodium Polystyrene Sulfonate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.