Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Capecitabine is used in dog for Carcinomas / oral fluoropyrimidine (investigational), Mammary carcinoma adjuvant (investigational). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Capecitabine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Xeloda
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 200–300 mg/kg | 200-300mg/m2 PO q12h, 14 days on / 7 days off | Monitor CBC and for GI toxicity | Carcinomas / oral fluoropyrimidine (investigational) | Anecdotal | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
| PO | 200–250 mg/kg | 200-250mg/m2 PO q12h, 14 days on / 7 days off | 6 cycles; assess response with imaging | Mammary carcinoma adjuvant (investigational) | Anecdotal | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Oral prodrug of 5-fluorouracil. Converted to 5-FU preferentially in tumor tissue via thymidine phosphorylase, providing tumor-selective activation.
CONTRAINDICATED IN CATS — metabolized to 5-FU which is lethal to felines. GI toxicity and hand-foot syndrome in humans. Very limited canine data. Handle with extreme caution around cats.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Capecitabine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.