Bleomycin for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Bleomycin is used in dog for Squamous cell carcinoma / testicular tumors. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Bleomycin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Blenoxane
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 10 mg/kg | IV q7-21 days (10 units/m2) | Cumulative dose limit; monitor pulmonary function | Squamous cell carcinoma / testicular tumors | Weak | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Generates free radicals that cause DNA strand breaks and inhibit DNA synthesis. Cell cycle specific for G2 and M phases. Concentrated in skin and lung tissue.
Side effects & warnings
Pulmonary fibrosis is dose-limiting and potentially fatal. Cumulative dose limit. Anaphylaxis risk — test dose recommended. Intralesional use for squamous cell carcinoma in cats.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Oncology drugs with dog dosing
Bleomycin dosing in other species
Why a species-specific page? Bleomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.