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Interferon Alpha (Feline) for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Interferon Alpha (Feline) is used in dog for Immune-mediated disease adjunct. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Interferon Alpha (Feline) in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Roferon-A, Intron A

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0 MU/kgq24hLong-term low-dose therapyImmune-mediated disease adjunctWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Binds to interferon receptors, activating antiviral and immunomodulatory pathways including natural killer cell activation and MHC upregulation.

Side effects & warnings

Fever and malaise common. Neutralizing antibodies may develop. Low-dose oral protocol is empirical. Human recombinant form used off-label.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Oncology drugs with dog dosing

Interferon Alpha (Feline) dosing in other species

Why a species-specific page? Interferon Alpha (Feline) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.